tecovirimat will enhance the level or result of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Use Warning/Observe. Tecovirimat can be a weak inhibitor of CYP2C8 and CYP2C19. Check for adverse outcomes if coadministered with delicate substrates of these enzymes.
Adjunct use, if apprehension, stress and anxiety or acute tension reactions existing previous to endoscopic methods
These severe side effects may also include things like delirium, paranoia, suicidal feelings or steps, seizures, and issue respiratory. Simply call your Health care supplier or head to the closest clinic emergency space right away if you will get any of such serious Unwanted effects.
Muscle spasms; convulsions caused by epilepsy or fever; anxiousness; agitation or sleeplessness related to stress and anxiety; panic attacks; like a pre-med before operation or clinical strategies; along with other remedies in Alcoholic beverages withdrawal
Coadministration of other CNS depressants or Liquor consumption might potentiate CNS-depressant outcomes of diazepam
Watch Carefully (one)larotrectinib will boost the degree or outcome of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check. Strong or average CYP3A4 inhibitors might minimize price of diazepam elimination, thereby growing more info adverse reactions to diazepam.
Coadministration of encorafenib with sensitive CYP3A4 substrates might result in enhanced toxicity or lowered efficacy of these brokers.
diazepam will boost the stage or result of midazolam intranasal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. Coadministration of moderate CYP3A4 inhibitors with midazolam intranasal may result in higher midazolam systemic publicity, which may prolong sedation.
diazepam will boost the level or impact of finerenone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Closely. Keep an eye on serum potassium throughout initiation and dosage adjustment of both finererone or weak CYP3A4 inhibitors. Alter finererone dosage as wanted.
VALTOCO is the one prescription nasal spray made use of to right away handle episodes of Regular seizures in Grown ups and youngsters six yrs and more mature. It’s distinctive from your daily anti-seizure medicines—you employ VALTOCO only when required.
VALTOCO provides precisely the same diazepam given that the rectal gel trusted by care companions, without the uncomfortable shipping.
Oral: Data not available No dose adjustment recommended Until administered for extended period; reduce dose in extended periods
nifedipine will boost the amount or result of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
eslicarbazepine acetate will lessen the extent or outcome of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.